Hi
While designing only you need to take care small things like changing width, padding, margin,
After that also if not fixed you can write different style sheet for that
<link href="homeoutside/formozilla.css" rel="stylesheet" type="text/css" />
<!--[if IE 6]>
<link href="homeoutside/forie.css" rel="stylesheet" type="text/css" />
<![endif]-->
<!--[if IE 7]>
<link href="homeoutside/forie7.css" rel="stylesheet" type="text/css" />
<![endif]-->
Like this
Regards
Jun 3, 2012