Drug Shows First Potential Treatment For Common Anaemia

Friday, 29 August 2014, 09:57 Hrs
cmt right
Comment Right
cmt right
cmt right
Printer Print Email Email

WASHINGTON: An experimental drug designed to help regulate the blood's iron supply shows promise as a viable first treatment for anaemia of inflammation.

The present treatment strategy for anaemia of inflammation targets the underlying disease or infection.

But recent research has sought to explore additional options for patients whose inflammation is difficult to control or when the cause of inflammation is unknown.

Hepcidin, which is the principal regulator of iron, has drawn a lot of attention from researchers developing novel therapies for blood disorders.

One hepcidin inhibitor, called lexaptepid pegol (lexaptepid) has shown efficacy in treating anaemia of inflammation in animal studies and now researchers have tried the experiment in human beings.

Lexaptepid inactivates hepcidin, thereby maintaining the transport of iron to the bloodstream.

"It is quite encouraging that lexaptepid helped maintain appropriate levels of iron in the bloodstream of healthy volunteers without compromising the immune response," said Lucas van Eijk of Radboud University Medical Center in Nijmegen, the Netherlands.

The results appeared in Blood Journal of American Society of Hematology.

Read More: Celebrities Replaced By Products For Endorsements and The 10 Most World-Changing Ads

Source: IANS
The Pentagon has selected Microsoft and Amazon Web Services (AWS, the cloud computing arm ..
The Reserve Bank of India injected a total liquidity of Rs 2.98 lakh crore in the market in 20..
US Indian
Facebook-owned photo messaging app Instagram has launched the beta version of its in-app sh..
Enterprise IT
Taking on streaming giants like Netflix and Hulu, Walt Disney Co. has announced it will laun..
"Game of Thrones" author George R.R. Martin doesn't want season eight to be the final chapter of "..
Wiley, a global leader in research and education has announced a series of blended learning progr..
Facebook-owned messaging app WhatsApp is still developing its previously announced "Vacatio..
Startup City
Youth are leading India's start-up ecosystem where the median age of founder-entrepreneurs..
Google Pixel and OnePlus smartphones are catching up and giving stiff competition to Samsu..