Brain Chemical Linked To Sleeplessness Identified

Thursday, 30 July 2015, 11:18 Hrs
35
cmt right
33
Comment Right
63
cmt right
13
cmt right
Printer Print Email Email


LONDON: Researchers have identified a brain chemical absence of which can lead to hyperactivity and sleeplessness.



In the experiments, mice without the GABA (gamma-aminobutyric acid) chemical developed characteristics similar to a medical condition called mania, in which patients experience restlessness and sleeplessness, the study noted.



This discovery could help researchers to develop new drugs that promote better sleep, or control hyperactivity in people with the medical condition mania.



“Sleep is essential for health. We have to do it every day. But nobody yet knows why,” said one of the lead researchers Bill Wisden, professor at Imperial College London.



The chemicals they studied, histamine and GABA, are produced in a primitive part of the brain that is highly similar in mice and humans.



The researchers found that GABA and histamine are made in the same brain cells, called histamine neurons.



They altered the levels of the GABA produced by the mice’s brains and measured what changes this had on their brain activity over the day and night.



The scientists found that compared with normal mice, those without GABA ran twice as far and twice as fast, and maintained or even increased their overall activity over a 30 minute period.



“What particularly surprised us was how little the mice were affected by sleep deprivation,” Nick Franks, professor at Imperial College London, pointed out.



The findings were detailed in the journal Neuron.
Also Read:
New Therapy Slows Down Brain Tumour
A Good Night's Sleep Sharpens Our Memories


Source: IANS
SPOTLIGHT
Gadgets
Google Pixel and OnePlus smartphones are catching up and giving stiff competition to Samsu..
Enterprise IT
Taking on streaming giants like Netflix and Hulu, Walt Disney Co. has announced it will laun..
Entertainment
"Game of Thrones" author George R.R. Martin doesn't want season eight to be the final chapter of "..
US Indian
Facebook-owned photo messaging app Instagram has launched the beta version of its in-app sh..
Technology
Facebook-owned messaging app WhatsApp is still developing its previously announced "Vacatio..
Career
Wiley, a global leader in research and education has announced a series of blended learning progr..
Startup City
Youth are leading India's start-up ecosystem where the median age of founder-entrepreneurs..
Finance
The Reserve Bank of India injected a total liquidity of Rs 2.98 lakh crore in the market in 20..
Business
The Pentagon has selected Microsoft and Amazon Web Services (AWS, the cloud computing arm ..