Immune Cells Govern Response to Alcohol

Friday, 30 September 2011, 09:35 Hrs
Printer Print Email Email
Sydney: Your immune cells could be governing your response to alcohol -- a finding that could help reduce alcohol dependence.

Mark Hutchinson, research fellow at the University of Adelaide School of Medical Sciences, said his team has come up with evidence that an immune response in the brain was involved in responses to alcohol.

This immune response lies behind alcohol-related behavioural changes, such as difficulty in walking and talking, the British Journal of Pharmacology reports.

"Alcohol is consumed annually by two billion people worldwide with its abuse posing a significant health and social problem," said Hutchinson, who led the study. "Over 76 million people are diagnosed with an alcohol abuse disorder."

"This work has significant implications for our understanding of the way alcohol affects us... It could lead to a way of detecting people who are at greater risk of developing brain damage after long-term drinking," said Hutchinson, according to an Adelaide statement.

Researchers studied the effects of giving alcohol to genetically altered mice. "The results showed that blocking a part of the immune system, either with the drug or genetically, reduced the effects of alcohol," Hutchinson said.

He believes similar treatment could work in humans. "Medications targeting this specific receptor -- toll-like receptor 4 -- may prove beneficial in treating alcohol dependence and acute overdoses," Hutchinson said.
Source: IANS
SPOTLIGHT
Business
The Pentagon has selected Microsoft and Amazon Web Services (AWS, the cloud computing arm ..
Technology
Facebook-owned messaging app WhatsApp is still developing its previously announced "Vacatio..
Career
Wiley, a global leader in research and education has announced a series of blended learning progr..
Startup City
Youth are leading India's start-up ecosystem where the median age of founder-entrepreneurs..
Enterprise IT
Taking on streaming giants like Netflix and Hulu, Walt Disney Co. has announced it will laun..
US Indian
Facebook-owned photo messaging app Instagram has launched the beta version of its in-app sh..
Gadgets
Google Pixel and OnePlus smartphones are catching up and giving stiff competition to Samsu..
Entertainment
"Game of Thrones" author George R.R. Martin doesn't want season eight to be the final chapter of "..
Finance
The Reserve Bank of India injected a total liquidity of Rs 2.98 lakh crore in the market in 20..