Genetic Mutation Allowed Humans To Digest Alcohol

NEW YORK: Human ancestors began evolving the ability to digest alcohol about 10 million years ago, researchers say.

The study found that a single genetic mutation 10 million years ago endowed human ancestors with an enhanced ability to break down ethanol.

Ethanol is found in rotting fruit and is also used in liquor and fuel.

The ability to break down alcohol likely helped human ancestors make the most out of rotting, fermented fruit that fell onto the forest floor, the researchers said.

Therefore, knowing when this ability developed could help researchers figure out when these human ancestors began moving to life on the ground, as opposed to mostly in trees, as earlier human ancestors had lived, 'LiveScience' reported.

Lead study author Matthew Carrigan at Santa Fe College in Gainesville, Florida and his team focused on the genes that code for a group of digestive enzymes called the ADH4 family.

ADH4 enzymes are found in the stomach, throat and tongue of primates, and are the first alcohol-metabolising enzymes to encounter ethanol after it is imbibed.

The researchers investigated the ADH4 genes from 28 different mammals, including 17 primates. They collected the sequences of these genes from either genetic databanks or well-preserved tissue samples.

READ MORE: Boys More Relationally Aggressive Than Girls and Stylish Winter Watches Women Should Get Hold Of