Washington: An Indian-American teenager has won a prestigious Science talent competition in the US for his research on devising a more effective and less toxic breast cancer treatment, walking away with a whooping $ 100,000.

Nithin Reddy Tumma topped the Intel Science Talent search that also saw two other Indian Americans - Neel Patel from Florida and Anirudh Prabhu from Indiana - finding a place in the top 10.

The winners overcame tough competition from a group of 40 finalists to what is touted as the toughest national science competition. Seven of them were Indian Americans.

Tumma, 17, from Michigan, won the top award from the Intel Foundation for his research on cancer.

He analysed the molecular mechanisms in cancer cells and found that by inhibiting certain proteins, we may be able to slow the growth of cancer cells and decrease their malignancy.

Nithin is first in his class of 332, a varsity tennis player and a volunteer for the Port Huron Museum, where he started a restoration effort for historical and cultural landmarks.

Second place was won by Andrey Sushko, 17, of Washington State, for his development of a tiny motor, only 7 mm in diameter, which uses the surface tension of water to turn its shaft. He received $ 75,000.

The third place of $ 50,000 went to Mimi Yen, 17, of Brooklyn, for her study of evolution and genetics, which focuses on microscopic worms, specifically looking at their sex habits and hermaphrodite tendencies.

Placed sixth, Neel Patel of Florida received a $ 25,000 award for studying how non-speech patterns of sounds - called sonifications - can convey information, which could lead to a computer-user interface as revolutionary as the graphical interface was 30 years ago.

Prabhu from Indiana received a $ 25,000 for the seventh spot for his investigation of the odd perfect number problem, and his suggestion that odd perfect numbers do not exist.

Earlier in the day, these 40 finalists met US President Barack Obama, at the White House.