He received a BSc from the University of Madras, a BE from the Indian Institute of Science, an MTech from the Indian Institute of Technology, and a PhD from the University of Ottawa, Canada.

Panchanathan has held a number of positions at Arizona State University since 1998.

He has been a foundation chair professor in Computing and Informatics since 2009 and a founding Director of the Centre for Cognitive Ubiquitous Computing since 2001.

Panchanathan founded the ASU School of Computing and Informatics in 2006 and the Department of Biomedical Informatics in 2005.

Prior to working for ASU, Panchanathan served at the University of Ottawa as a founding Director of the Visual Computing and Communications Laboratory from 1990 to 1997.

He worked as Associate Professor in the Department of Electrical and Computer Engineering from 1994 to 1997, and Assistant Professor from 1989 to 1994.
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