Kidney cells could help do away with transplants

Thursday, 28 July 2011, 11:54 Hrs
Printer Print Email Email
Sydney: Around 60 million people worldwide have chronic kidney disease and many need dialysis or transplants. But thanks to a vital breakthrough, patients' own kidney cells collected from urine can now be reprogrammed to make these procedures redundant.

Such reprogramming could mean that in future, fewer kidney patients would require complicated, expensive procedures that affect their quality of life. There are around 88,000 patients waiting for a kidney transplant in the US, for as long as three to five years.

Sharon Ricardo from Monash University and her colleagues took cells from an individual's kidney and coaxed them to become progenitor cells, allowing the immature cells to form any type in the kidney, the Journal of the American Society Nephrology reports.

Specifically, they inserted several key reprogramming genes into the renal cells that made them capable of forming other cells, according to a Monash University statement.

In a second study, Miguel Esteban, from the Chinese Academy of Sciences, China and colleagues found that kidney cells collected from a patient's urine can also be reprogrammed in this way.

Using cells from urine allows a technology easy to implement in a clinic setting. Even better, urine cells could be frozen and later thawed before they are manipulated.

Besides providing a potentially curative therapy for patients, the breakthroughs might also help investigators study the causes of kidney disease and screen new drugs that could be used to treat them.
Source: IANS
Hinduja Global Solutions here on Monday said it has set up a centre of excellence to train disable..
The Department of Telecommunications (DoT) in consultation with the Finance Ministry plans to spli..
US Indian
An Indian-American teenager has been conferred with the 2019 National STEM (Science, Technolog..
Startup City
India Accelerator, a GAN partnered, mentorship-driven, acceleration program hosted ‘The Inner Ci..
First things first. "Made In Heaven" is the sexiest webseries India has produced, no doubt about i..
Facebook ruled out a cyber attack on its products Whatsapp, Instagram and Messenger, which suffere..
Chipset-making giant Qualcomm has listed chipsets such as Snapdragon 855, 845, 710, 675 and 67..
IIT Roorkee organized an MoU exchanging ceremony between the Govt. of India Department of Scie..
Enterprise IT
PayByPhone, the global leader in mobile parking payments, today announced that it will appoint And..